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A Graphene Nanoprobe for Rapid, Sensitive, and Multicolor Fluorescent DNA Analysis

✍ Scribed by Shijiang He; Bo Song; Di Li; Changfeng Zhu; Wenpeng Qi; Yanqin Wen; Lihua Wang; Shiping Song; Haiping Fang; Chunhai Fan

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
668 KB
Volume
20
Category
Article
ISSN
1616-301X

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## Abstract A new strategy for highly sensitive and rapid protease assay is developed by mediating proteolytic formation of oligonucleotide duplexes and using the duplexes for signal amplification. In the presence of matrix metalloprotease‐2 (MMP‐2), fragmentation of the intact DNA–peptide on gold