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A rapid and sensitive liquid chromatographic assay for epoxide hydrase

โœ Scribed by S. Nesnow; C. Heidelberger


Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
300 KB
Volume
67
Category
Article
ISSN
0003-2697

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โœฆ Synopsis


A rapid method for the assay of epoxide hydrase activity is described. 3-Methylcholanthrene-11.1 Z-oxide is employed as substrate and high speed liquid chromatography is used to separate and quantitate tram-11. I ?-dihydro-I 1.12dihydroxy-3-methylcholanthrene (product) formation. The determination of product at picomole levels can be obtained.


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