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A rapid and convenient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2-ones and thiones

✍ Scribed by Zhanxiong Fang; Yulin Lam


Book ID
108283473
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
190 KB
Volume
67
Category
Article
ISSN
0040-4020

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## Abstract A general and convenient route for the synthesis of dihydropyrimidines bearing the phosphoryl moiety by a one‐pot cyclocondensation involving aldehydes, urea, and O,O‐dialkyl‐2‐oxo‐propanephosphonates, using ytterbium triflate as catalyst, is reported. Β© 2003 Wiley Periodicals, Inc. Het