## Abstract ## BACKGROUND The treatment of patients with hepatocellular carcinoma (HCC) presents a major challenge, because associated cirrhosis limits the choice of chemotherapeutic agents. However, the abundant vascularity of HCC presents an attractive target for antiangiogenic therapy that pote
โฆ LIBER โฆ
A randomized multicenter phase II clinical trial of mitoxantrone-loaded nanoparticles in the treatment of 108 patients with unresected hepatocellular carcinoma
โ Scribed by Qinghua Zhou; Xun Sun; Lingyuan Zeng; Jie Liu; Zhirong Zhang
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 151 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1549-9634
No coin nor oath required. For personal study only.
โฆ Synopsis
From the clinical editor:
Intravenous administration of mitoxantrone-loaded polybutylcyanacrylate nanoparticles (dhad-pbca-nps) allows increased cytotoxicity in hepatic tumors and prolonged the median survival periods to 5.46 months compared to 3.23 months in controls.
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