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A multi-centre randomized phase II study of nolatrexed versus doxorubicin in treatment of Chinese patients with advanced hepatocellular carcinoma

✍ Scribed by Tony S. K. Mok; Thomas W. T. Leung; Shou-Dong Lee; Yee Chao; Anthony T. C. Chan; Andrew Huang; Mei-Ching Lui; Winnie Yeo; Karen Chak; Amanda Johnston; Philip Johnson

Publisher
Springer
Year
1999
Tongue
English
Weight
79 KB
Volume
44
Category
Article
ISSN
0344-5704

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## BACKGROUND. Inoperable hepatocellular carcinoma is an incurable malignancy with no accepted standard therapy. Chemotherapy has demonstrated occasional responses and the need is great for a new and effective agent. Therefore the authors conducted this Phase II trial of a novel thymidylate syntha