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A randomised cross-over trial comparing low-dose metoclopramide and chlorpromazine with high-dose metoclopramide in Chinese patients with advanced cancer receiving cisplatinum and 5-fluorouracil

✍ Scribed by Wesely Shiu; Victor Tsang; Yuk M. Lam; Alex Zacharia; W. M. Craig Martin

Book ID
104813590
Publisher
Springer
Year
1987
Tongue
English
Weight
326 KB
Volume
20
Category
Article
ISSN
0344-5704

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Background. In a previous Phase I1 trial, the authors showed that a weekly continuous infusion of 5-fluorouracil (5-FU) at a dose of 3.5 g/mz for 48 hours is an active treatment for advanced colorectal cancer. The overall response rate was 38.5%, and the median survival was 12 months. These data wer