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A radioenzymatic assay for catecholamines and dihydroxyphenylacetic acid

✍ Scribed by Charles F. Saller; Michael J. Zigmond

Book ID
118938503
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
815 KB
Volume
23
Category
Article
ISSN
0024-3205

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A new and rapid method for the determination of the excitotoxic tryptophan metabolite quinolinic acid is based on its enzymatic conversion to nicotinic acid mononucleotide and, in a second step utilizing ['H]ATP, further to ['HI deamido-NAD. Specificity of the assay is assured by using a highly puri