A rabbit ear model for cold stress testing

✍ Scribed by Dr. Thomas L. Smith; Stanley Gordon; Martha B. Holden; Beth P. Smith; Gregory B. Russell; L. Andrew Koman

• Publisher: John Wiley and Sons
• Year: 1994
• Tongue: English
• Weight: 407 KB
• Volume: 15
• Category: Article
• ISSN: 0738-1085
• DOI: 10.1002/micr.1920150808

✦ Synopsis

Abstract

A rabbit ear model resembling the human digit was studied to determine the vascular response of the rabbit ear to a cold stress. Following moderate cooling (10 minutes at 5°–8°C), auricular blood flow and cutaneous perfusion were reduced. This decrease was reversed by 30 minutes of warming. The response in the rabbit ear to cold stress is similar to that of normal human digits. The similarities between the control of the circulation in human digits and rabbit ears may result from the similarities in digital and auricular vascular receptors and receptor subtypes. Verification of the rabbit model provides an experimental method for obtaining important data regarding digital pathophysiology and the treatment of cold intolerance. Further study with this model will provide clinically relevant information regarding the pathophysiology of digital thermoregulatory abnormalities. © 1994 Wiley‐Liss, Inc.