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A Quarter Century of Thalidomide Embryopathy

✍ Scribed by Mitsushiro KIDA

Book ID
114824995
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
415 KB
Volume
28
Category
Article
ISSN
0914-3505

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πŸ“œ SIMILAR VOLUMES

Hypothesis: Thalidomide embryopathy?prop
Hypothesis: Thalidomide embryopathy?proposed mechanism of action
✍ Stephens, Trent D.; Fillmore, Bradley J. πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 98 KB πŸ‘ 1 views

We propose that thalidomide affects the following pathway during limb development: Growth factors (FGF-2 and IGF-I) attach to receptors on limb bud mesenchymal cells and initiate some second messenger system (perhaps SP-1), which activates ␣v and ␀3 integrin subunit genes. The resulting ␣v ␀3 integr

New cases of thalidomide embryopathy in
New cases of thalidomide embryopathy in Brazil
✍ Lavinia Schuler-Faccini; Rosa Castalia Franca Soares; Artur Custodio Moreira de πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 47 KB

## Abstract Thalidomide is the best known human teratogen. Although withdrawn from the market in 1961, thalidomide was remarketed after 1965 in several countries, for the treatment of erythema nodosum leprosum. Thalidomide has a potent immunomodulatory property and has now a number of approved and

A QUARTER CENTURY
A QUARTER CENTURY
✍ PAUL B. PEARSON πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 61 KB