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A quantitative stereoselective synthesis of radiolabelled PGF2α from arachidonate or PGE2

✍ Scribed by K. J. Stone; M. Hart


Publisher
John Wiley and Sons
Year
1976
Tongue
French
Weight
418 KB
Volume
12
Category
Article
ISSN
0022-2135

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✦ Synopsis


Abstract

A simple, efficient and relatively cheap procedure for synthesising radiolabelled PGF~2α~ from arachidonate or PGE~2~ is described. The method exploits the stereospecific enzymatic reduction of PGE~2~ by PGE~2~‐9‐ketoreductase from rabbit renal cortex.


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