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A quantitative competitive PCR assay for the covalently closed circular form of the duck hepatitis B virus

✍ Scribed by William R Addison; Winnie W.S Wong; Karl P Fischer; D.Lorne J Tyrrell

Book ID
114144107
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
344 KB
Volume
48
Category
Article
ISSN
0166-3542

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## Abstract Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) serves as a template for viral replication and plays a role in persistence of HBV infection. The origin and significance of cccDNA in plasma however, is not well understood. A sensitive, specific, and reproducible real‐time