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A qualitative molecular mechanics approach to the stereoselectivity of intramolecular Pauson-Khand reactions

✍ Scribed by Jaume Castro; Albert Moyano; Miquel A. Pericàs; Antoni Riera


Book ID
107857557
Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
959 KB
Volume
51
Category
Article
ISSN
0040-4020

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An intramolecular Pauson–Khand approach
✍ Ramon Rios; Albert Moyano; Miquel A Pericàs 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 98 KB

A procedure for the synthesis of chirally-substituted cyclopentadienes has been developed by employing the intramolecular Pauson-Khand reaction of chiral amides derived from 8-nonen-2-ynoic acid. Hydride-mediated reduction of the resulting cyclopentenone adducts followed by acid-catalysed dehydratio