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A QSAR study and molecular design of benzothiazole derivatives as potent anticancer agents

✍ Scribed by JinCan Chen; Li Qian; Yong Shen; LanMei Chen; KangCheng Zheng


Book ID
107348625
Publisher
SP Science China Press
Year
2008
Tongue
English
Weight
275 KB
Volume
51
Category
Article
ISSN
1674-7291

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Synthesis and biological evaluation of b
✍ Masao Yoshida; Ichiro Hayakawa; Noriyuki Hayashi; Toshinori Agatsuma; Youko Oda; πŸ“‚ Article πŸ“… 2005 πŸ› Elsevier Science 🌐 English βš– 259 KB

Based on 2-methyl-4-nitro-2H-pyrazole-3-carboxylic acid[2-(cyclohexanecarbonylamino)benzothiazol-6-yl]amide (1), which shows selective cytotoxicity against tumorigenic cell lines, 2,6-dichloro-N-[2-(cyclopropanecarbonylamino)benzothiazol-6yl]benzamide (13b) was designed and synthesized as a biologic