A Theoretical Experimental Method to Det
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E. Buchman; H. Parnas
📂
Article
📅
1999
🏛
Springer
🌐
English
⚖ 320 KB
Consider a ligand-gated channel with n agonist binding sites which can undergo desensitization. We present a theoretical experimental procedure for pinpointing the principal receptor state from which there is a transition to the desensitized state. The method is based on the observation that the dep