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A Proposed Mechanism for the Induction of Cytotoxic T Lymphocyte Production by Heat Shock Fusion Proteins

✍ Scribed by Bryan K Cho; Deborah Palliser; Eduardo Guillen; Jan Wisniewski; Richard A Young; Jianzhu Chen; Herman N Eisen

Book ID: 117722608
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 174 KB
Volume: 12
Category: Article
ISSN: 1074-7613
DOI: 10.1016/s1074-7613(00)80179-x

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## Abstract Heat shock protein 90 (Hsp90) is an abundant protein and essential for all eukaryotic cells. The expression of Hsp90 is further enhanced after exposure to stress factors, e.g. a heat shock. Many proteins interacting with Hsp90 as well as the various functions for Hsp90 have been describ