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A progress report of a phase I study of interferon-gamma and interleukin-2 and some comments on the mechanism of the toxicity due to interleukin-2

✍ Scribed by Wagstaff, J.; Vermorken, J.B.; Schwartsmann, G.; Scheper, R.J.; Hack, C.E.; Nuijens, J.H.; Eerenberg-Belmer, A.J.M.; Pinedo, H.M.

Book ID: 123033928
Publisher: Elsevier Science
Year: 1989
Tongue: English
Weight: 296 KB
Volume: 16
Category: Article
ISSN: 0305-7372
DOI: 10.1016/0305-7372(89)90029-7

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## Abstract ## BACKGROUND The current study evaluated the efficacy and toxicity of interleukin‐2 (IL‐2), interferon‐α (IFN‐α), 5‐fluorouracil (5‐FU), and vinblastine (VBL) in the treatment of metastatic renal cell carcinoma (MRCC). ## METHODS Sixty‐two MRCC patients, median age 63 years, receive