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A procedure for the quantitative isolation of brain gangliosides

โœ Scribed by Lars Svennerholm; Pam Fredman


Book ID
115738087
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
1015 KB
Volume
617
Category
Article
ISSN
0005-2760

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A procedure for the preparation of a radioiodinated derivative of ganglioside GMl has been devised. Carbon 6 of the terminal galactosyl residue of GMI was converted to an aldehyde by galactose oxidase. The adduct formed by this oxidation product of GMI with tyramine was reduced with sodium cyanoboro