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A practical total synthesis of both enantiomers of epoxyquinols A and B

โœ Scribed by Mitsuru Shoji; Satoshi Kishida; Mitsuhiro Takeda; Hideaki Kakeya; Hiroyuki Osada; Yujiro Hayashi

Book ID
104252428
Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
94 KB
Volume
43
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

A practical total synthesis of both enantiomers of epoxyquinols A and B has been developed. Key reactions are the chromatography-free preparation of an iodolactone by using acryloyl chloride as dienophile in the Diels-Alder reaction of furan, the lipase-mediated kinetic resolution of a cyclohexenol derivative, and a modified procedure for a-iodonation of a cyclohexenone.

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