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A practical synthesis of the milbemycin SB-201561

✍ Scribed by Ian P Andrews; Roderick J.J Dorgan; Timothy Harvey; Joseph F Hudner; Nigel Hussain; David C Lathbury; Norman J Lewis; Graham S Macaulay; David O Morgan; Robert Stockman; Charles R White


Book ID
103408273
Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
126 KB
Volume
37
Category
Article
ISSN
0040-4039

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ChemInform Abstract: Practical Synthesis
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

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✍ Michael T. Crimmins; W.Gary Hollis Jr.; Danute M. Bankaitis-Davis πŸ“‚ Article πŸ“… 1987 πŸ› Elsevier Science 🌐 French βš– 287 KB

A highly stereocontrolled synthesis of the Cl 1 to C3 1 fragment of the potent antimicrobial agent milbemycin D has been completed. This approach utilizes a unique hydrolysis-cyclization to construct the spiroketal portion of the molecule. The milbemycins 2 and the avermectins3 are two structurall