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A Practical Synthesis of Pyrene-4,5-dione

โœ Scribed by Young, Erick R. R.; Funk, Raymond L.


Book ID
126014450
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
24 KB
Volume
63
Category
Article
ISSN
0022-3263

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The practical multigram synthesis of the title compound (IV) involves a crucial intramolecular acyloin condensation of the diester with excess sodium in refluxing THF. The dione (IV) is obtained in high yield after aerobic work-up. -(YOUNG, ERICK

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