✦ LIBER ✦

A practical solid phase synthesis of quinazoline-2,4-diones

✍ Scribed by Hui Shao; Marcus Colucci; Shaojing Tong; Hesheng Zhang; Arlindo L. Castelhano

Book ID: 108387033
Publisher: Elsevier Science
Year: 1998
Tongue: French
Weight: 219 KB
Volume: 39
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(98)01595-0

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Solid-phase synthesis of 1,3-dialkyl qui

Solid-phase synthesis of 1,3-dialkyl quinazoline-2,4-diones

✍ Brad O. Buckman; Raju Mohan 📂 Article 📅 1996 🏛 Elsevier Science 🌐 French ⚖ 205 KB

A general and efficient solid phase synt

A general and efficient solid phase synthesis of quinazoline-2,4-diones

✍ Mikhail F Gordeev; Hon C Hui; Eric M Gordon; Dinesh V Patel 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 252 KB

An efficient solid phase synthesis of chiral quinazolinediones is described. Immobilized amino acid based urea derivatives 3 undergo a racemization-free heterocyclization upon gentle heating in presence of tetramethylguanidinc to afford fused pyrimidine-2,4-diones 6, which are smoothly NJ-alkylated

Solid phase synthesis of chiral 3-substi

Solid phase synthesis of chiral 3-substituted quinazoline-2,4-diones

✍ Laurent Gouilleux; Jean-Alain Fehrentz; F. Winternitz; Jean Martinez 📂 Article 📅 1996 🏛 Elsevier Science 🌐 French ⚖ 213 KB

ChemInform Abstract: Solid-Phase Synthes

ChemInform Abstract: Solid-Phase Synthesis of Chiral 3-Substituted Quinazoline-2,4-diones.

✍ L. GOUILLEUX; J.-A. FEHRENTZ; F. WINTERNITZ; J. MARTINEZ 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views

Solid-Phase Synthesis of Chiral 3-Substituted Quinazoline-2,4-diones. -A series of N-urethane precursors such as (I) or (III) are prepared and subjected to cyclization in the presence of base (DBU, NaOH or NEt3). The desired quinazolines are obtained in good to excellent yield without racemization.

Efficient solid-phase synthesis of quina

Efficient solid-phase synthesis of quinazoline-2,4-diones with various substituents on aromatic rings

✍ Tatsuya Okuzumi; Eiji Nakanishi; Takashi Tsuji; Shingo Makino 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 200 KB

We have developed a method for the solid-phase synthesis of quinazoline-2,4-diones with various substituents on the aromatic ring. Although there have been numerous reports of the solid-phase synthesis of quinazoline-2,4-diones, they were not applicable to the synthesis of the quinazoline-2,4-diones

Solid-phase synthesis of 5,6-dihydropyri

Solid-phase synthesis of 5,6-dihydropyrimidine-2,4-diones

✍ Stephen A. Kolodziej; Bruce C. Hamper 📂 Article 📅 1996 🏛 Elsevier Science 🌐 French ⚖ 234 KB