A practical synthesis of N-hydroxy-α-amino acid esters
✍ Scribed by J.D.M. Heracheid; H.C.J. Ottenheijm
- Book ID
- 108384682
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- French
- Weight
- 141 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
Chloromethylation of N-imine-protected amino acid esters followed by acid hydrolysis gave a-aminoalkyl-a%chloromethylketone as a HCl salt form in good yield without racemization. The amino group was conveniently protected with carbamate protecting reagents to give various useful intermediates for th
## Abstract 3‐Aryl‐3‐azido‐2‐hydroxypropanoic esters, prepared from the corresponding 3‐aryl‐oxirane‐2‐carboxylic esters by ring opening with sodium azide, were reduced with tin(II) chloride dihydrate in methanol to give 3‐amino‐3‐aryl‐2‐hydroxypropanoic esters in good yields. Under these condition