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A Practical Synthesis of 4-(Substituted-benzyl)piperidines and (±)-3-(Substituted-benzyl)pyrrolidines via a Wittig Reaction

✍ Scribed by Zhou, Zhang-Lin; Keana, John F. W.


Book ID
120508254
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
53 KB
Volume
64
Category
Article
ISSN
0022-3263

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Synthesis of Phenyl- and Benzyl-Substitu
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## Abstract The construction of new or novelly functionalized annulated and bridged tricylic compounds by two consecutive C,C‐bond formations (a and b in **la**, __Scheme 1__) is described. In a first step, chloroalkyl‐substituted aminonitriles yielded pyrrolidines **8**, **15a**, **15b**, **23**,