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A practical preparation of aryl β-ketophosphonates

✍ Scribed by Robert R. Milburn; Ken McRae; Johann Chan; Jason Tedrow; Robert Larsen; Margaret Faul


Book ID
104096076
Publisher
Elsevier Science
Year
2009
Tongue
French
Weight
142 KB
Volume
50
Category
Article
ISSN
0040-4039

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✦ Synopsis


The condensation of alkyl phosphonates with aryl esters to give b-ketophosphonates may be carried out at elevated temperatures mediated by LiHMDS under Barbier type conditions. The reaction is scalable, does not require specialized cryogenic equipment, and is general for all aryl and heteroaryl esters examined.


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ChemInform Abstract: A Practical Prepara
✍ Robert R. Milburn; Ken McRae; Johann Chan; Jason Tedrow; Robert Larsen; Margaret 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 34 KB

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