A General Procedure for the Preparation of β-Ketophosphonates
✍ Scribed by Maloney, Kevin M.; Chung, John Y. L.
- Book ID
- 119993848
- Publisher
- American Chemical Society
- Year
- 2009
- Tongue
- English
- Weight
- 755 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
The condensation of alkyl phosphonates with aryl esters to give b-ketophosphonates may be carried out at elevated temperatures mediated by LiHMDS under Barbier type conditions. The reaction is scalable, does not require specialized cryogenic equipment, and is general for all aryl and heteroaryl este
## Abstract The α and β hydrogen exchange reactions catalyzed by pyridoxal have been applied to ten of the common amino acids to prepare α, β deuterated derivatives. The exchange and isolation procedure allows for numerous different samples to be processed in parallel. The deuteration at the α posi
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