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A practical one-pot synthesis of 2,3-disubstituted indoles from unactivated anilines

✍ Scribed by Makoto Tokunaga; Mitsuru Ota; Masa-aki Haga; Yasuo Wakatsuki


Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
69 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis


2-Substituted-3-methyl indoles are synthesized with good regioselectivity from readily available substrates and catalysts, i.e. the reaction of anilines with propargyl alcohols in the presence of 0.36-1 mol% Ru 3 (CO) 12 .


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