A practical method for the preparation o
✍
Ping Chen; Peter T.W. Cheng; Steven H. Spergel; Robert Zahler; Xuebao Wang; John
📂
Article
📅
1997
🏛
Elsevier Science
🌐
French
⚖ 230 KB
A practical method for the preparation of ot-N-BOC-epoxides from protected amino acid esters based on the Kowalski homologation reaction is described. This procedure can be readily performed on a large scale without the use of hozardous reagents and has aUowed preparation of epoxides 3 in multi-kilo