A Practical NMR-Based High-Throughput As
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Manfredβ
T. Reetz; Andreas Eipper; Patrick Tielmann; Richard Mynott
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Article
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2002
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John Wiley and Sons
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English
β 148 KB
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Two NMR-based approaches for highthroughput screening of enantioselective catalysts and biocatalysts are described. One version makes use of pseudo-enantiomers or pseudo-meso-compounds based on 13 C-labeling. A throughput of at least 1400 ee determinations per day is possible by using an appropriate