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A practical approach for optimization of a selective gas-chromatographic detector by a sequential simplex method

✍ Scribed by Hsu, F. ;Anderson, J. ;Zlatkis, A.

Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
229 KB
Volume
3
Category
Article
ISSN
0935-6304

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✦ Synopsis

approximate movement of the plunger during packing is 40 mm. The diagram (Figure 1) is to scale, except for the O-rings, valves and tube fittings. Packing with this system wassatisfactoryexcept when we failed to add enough packing material to fill the column completely, or when the stirring bar failed because of insufficient magnetic coupling. The latter problem was solved by replacing the origingal flat-plate magnetic stirrer with an Alnico U-magnet. The volume occupied by the stirring bar does require that excess packing material be used, a disadvantage with expensive materials. This system would appear to be particularly suitable for the upward slurry packing of larger columns, since the rate of extrusion of the slurry would not be limited by the speed of a pump. It appears that scale-up is possible, as long as pressure ratings are observed for all compooents. MS

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