A Practical Asymmetric Synthesis of Enan
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Vadim A. Soloshonok; Chaozhong Cai; Victor J. Hruby
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Article
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2000
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John Wiley and Sons
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English
โ 103 KB
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In recent years, tailor-made c-constrained amino acids have emerged as critically important key structural units in the de novo design of peptide-based drugs with enhanced receptor selectivity and stability to metabolic degradation. [1, Incorporation of these amino acids in strategic positions of a