A possible involvement of type II cAMP-dependent protein kinase in the initiation of DNA synthesis by rat liver cells
β Scribed by A.L. Boynton; J.F. Whitfield
- Book ID
- 118877667
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- English
- Weight
- 469 KB
- Volume
- 126
- Category
- Article
- ISSN
- 0014-4827
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## Abstract The brief rise in the cellular cyclic AMP content which occurs late in the prereplicative phases of rat hepatocytes in vivo and T51B rat liver epitheloid cells in vitro seems to be necessary for the initiation of DNA synthesis. Thus, the extracellular calciumβdeprivation in T51B rat liv
## Abstract Changing the medium, or adding fresh serum, induces a large proportion of the proliferatively quiescent cells in confluent monolayers of human WIβ38 and mouse BALB/3T3 cells to initiate a growthβdivision cycle. Exposure at the time of the medium change or serum addition to MGBG (methyl