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A Population Pharmacokinetic and Pharmacodynamic Evaluation of Pralatrexate in Patients With Relapsed or Refractory Non-Hodgkin's or Hodgkin's Lymphoma

✍ Scribed by O'Connor, O A; Mould, D R; Sweeney, K; Duffull, S B; Neylon, E; Hamlin, P; Horwitz, S; Sirotnak, F; Fleisher, M; Saunders, M E


Book ID
109845963
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
275 KB
Volume
86
Category
Article
ISSN
0009-9236

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## Abstract The prognosis of relapsing Hodgkin's disease (HD) and high grade aggressive non‐Hodgkin's lymphoma (NHL) is generally poor since many of these patients fail to respond to second line chemotherapy. Radiation therapy has been reported as an effective but seldom used, alternative treatment