Radiotherapy as salvage treatment in patients with hodgkin's disease or non-hodgkin's lymphoma relapsing after initial chemotherapy
β Scribed by Carine Kirkove; Adrian R. Timothy
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 319 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0278-0232
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β¦ Synopsis
Abstract
The prognosis of relapsing Hodgkin's disease (HD) and high grade aggressive nonβHodgkin's lymphoma (NHL) is generally poor since many of these patients fail to respond to second line chemotherapy. Radiation therapy has been reported as an effective but seldom used, alternative treatment. We have observed very encouraging results with salvage radiotherapy in a highly selected group of eight lymphoma patients (six with HD and two with high grade NHL), suffering mainly from nodal relapse. The literature on the use of radiation therapy after chemotherapy failures in HD and NHL is reviewed.
π SIMILAR VOLUMES
We assessed the efficacy of an etoposide, ifosfamide and methotrexate combination therapy (VIM) in 24 patients failing the LNH 84 protocol. Eight of these patients were refractory to the LNH 84 induction regimen, 10 were partial responders and the six remaining attained complete response after LNH 8
## Abstract Forty patients with relapsed diffuse large B cell lymphoma (DLBCL) autografted in partial response (PR) (__n__β=β23) or in refractory relapse (RR) (__n__β=β17) achieved complete remission (CR) after autologous stem cell transplantation (ASCT). Salvage treatment consisted of ifosphamide,