Close genetic linkage has been shown between the DNA sequence G8 (locus D4S10) and 16 British families with Huntington disease using the HindIII, EcoR1, Nci1, and Pst1 polymorphisms detected by G8, and by combining all the polymorphisms to give a combined haplotype. Two recombinants have been detect
β¦ LIBER β¦
A polymorphic DNA marker genetically linked to Huntington's disease
β Scribed by Gusella, James F.; Wexler, Nancy S.; Conneally, P. Michael; Naylor, Susan L.; Anderson, Mary Anne; Tanzi, Rudolph E.; Watkins, Paul C.; Ottina, Kathleen; Wallace, Margaret R.; Sakaguchi, Alan Y.
- Book ID
- 109732701
- Publisher
- Nature Publishing Group
- Year
- 1983
- Tongue
- English
- Weight
- 878 KB
- Volume
- 306
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/306234a0
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