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A polymer-bound oxazaborolidine catalyst: Enantioselective borane reductions of ketones
✍ Scribed by Christelle Franot; Guy B. Stone; Peter Engeli; Christoph Spöndlin; Erwin Waldvogel
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 694 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0957-4166
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📜 SIMILAR VOLUMES
A polymer-enlarged homogeneously soluble oxazaborolidine catalyst has been prepared and used in the enantioselective borane reduction of ketones. The catalyst is derived from (2S,4R)-ot,ot-diphenyl-2-[(4-allyloxy)-N-benzyloxycarbonyl]pyrrolidinemethanol 3 and a methyl hydrosiloxane---dimethylsiloxan
## Abstract The effect of borane source on enantioselectivity in the enantiopure oxazaborolidine‐catalyzed asymmetric borane reduction of ketones has been investigated by using (__S__)‐3,1,2‐oxazaborobicyclo[3.3.0]octane and (__S__)‐7,3,1,2‐thiaxazaborobicyclo[3.3.0]octane as catalysts. The results