A polar substituent effect on the ring-cleavage rearrangement of 1-arylcyclobutylmethyl Grignard reagents
โ Scribed by E.Alexander Hill; Baoju Li
- Book ID
- 107812373
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 615 KB
- Volume
- 448
- Category
- Article
- ISSN
- 0022-328X
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๐ SIMILAR VOLUMES
Although the reaction of substituted fluoroolefins with nucleophiles, such as ethoxide, has received considerable attention in recent years (l), little is known concerning the subsequent attack by excess Grignard reagent on the initially formed substitution product in these systems.
The light induced ring closure of cycloheptatrienes to bicycle-[3,2,0]-hepta-2,6-dienes is generally directionally specific in those cases where theoretically two bicyclic products may be formed (1). We have recently rationalised this fact in terms of the effect of eubstituents on the dirdction of p