The combination of 5-fluorouracil and cisplatin has shown encouraging results in single institution pilot studies in colorectal carcinoma. This phase II SWOG study was undertaken to further evaluate this treatment. Cisplatin was administered at a dose of 60 mg/M2 IV day 1, repeated every 21 days. 5-
β¦ LIBER β¦
A pilot study of intraarterial chemotherapy (IAC) in metastatic colorectal carcinoma (CC)
β Scribed by Cyjon, A.; Neumann, M.; Sulkes, A.
- Book ID
- 123416902
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 160 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0959-8049
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Although intrahepatic infusion therapy with 5-fluorouracil for unresectable colorectal liver metastases may lead to improved overall survival for some patients, it is not clear why a response is not observed in others. Gene alterations in oncogenes or tumor-suppressor genes are critical events in tu