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A physiologically based biokinetic (PBBK) model for estragole bioactivation and detoxification in rat

✍ Scribed by Ans Punt; Andreas P. Freidig; Thierry Delatour; Gabriele Scholz; Marelle G. Boersma; Benoît Schilter; Peter J. van Bladeren; Ivonne M.C.M. Rietjens

Book ID
113924358
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
765 KB
Volume
231
Category
Article
ISSN
0041-008X

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📜 SIMILAR VOLUMES

In silico methods for physiologically ba
In silico methods for physiologically based biokinetic models describing bioactivation and detoxification of coumarin and estragole: Implications for risk assessment
✍ Ivonne M. C. M. Rietjens; Ans Punt; Benoît Schilter; Gabriele Scholz; Thierry De 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 331 KB

## Abstract In chemical safety assessment, information on adverse effects after chronic exposure to low levels of hazardous compounds is essential for estimating human risks. Results from __in vitro__ studies are often not directly applicable to the __in vivo__ situation, and __in vivo__ animal stu