A phase I–II study of epirubicin, 5-fluorouracil, and leucovorin in advanced adenocarcinoma of the stomach
✍ Scribed by Gabriela Kornek; Franz Schulz; Dieter Depisch; Harald Rosen; Werner Kwasny; Christian Sebesta; Werner Scheithauer
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 315 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0008-543X
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📜 SIMILAR VOLUMES
To determine the feasibility and toxicity of combining leucovorin (CF) with a 5fluorouracil(5-FU) combination chemotherapy regimen currently accepted by many as standard treatment for gastric cancer, CF (500 mg/m') was administered in combination with the Georgetown S-FU, doxorubicin, and mitomycin
In a Phase I1 study, 50 patients with advanced breast cancer were treated with a combination of 5fluorouracil(lOO0 mg/m2 on days 1 and 2) and mitomycin C (6 mg/m2 on day 2) (FuMi regimen). The courses were repeated every third to sixth week. Although 35 patients had previously received combination c
## BACKGROUND. Gastric carcinoma is a substantial health problem in Turkey, and the majority of patients present with inoperable disease. The aim of this randomized trial was to assess the activity of 5-fluorouracil versus etoposide when combined with epirubicin plus cisplatin in patients with adv