A phase II trial of cisplatin and prolonged administration of oral etoposide in extensive-stage small cell lung cancer
β Scribed by Patrick B. Murphy; John D. Hainsworth; F. Anthony Greco; Kenneth R. Hande; Russell F. Devore; David H. Johnson
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 582 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0008-543X
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π SIMILAR VOLUMES
## Abstract A phase II trial of etoposide and cisplatin for patients with previously treated small cell lung cancer was carried out by CALGB from June 1983 to May 1984. Thirtyβfive evaluable patients who had failed one prior chemotherapy regimen were treated with etoposide 80 mg/m^2^ and cisplatin
## Abstract There is no standard therapy for relapsed small cell lung cancer (rSCLC). We evaluated the efficacy and toxicity of a new triplet consisting of irinotecan (100 mg/m^2^ Days 1 and 15 q28), cisplatin (40 mg/m^2^ Days 1 and 15 q28) and mitomycin (6 mg/m^2^ d1 q28) administered to a maximum
## Abstract ## BACKGROUND The objective of this study was to test the response rate and toxicity of alternating chemotherapy in previously untreated patients with extensiveβstage small cell lung carcinoma (SCLC). ## METHODS Patients with histologically proven, extensiveβstage SCLC, with a perfor