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A Phase II Study of Intravenous Exatecan Mesylate (DX-8951f) Administered Daily for Five Days Every Three Weeks to Patients with Metastatic Adenocarcinoma of the Colon or Rectum

✍ Scribed by Melanie E. Royce; Eric K. Rowinsky; Paulo M. Hoff; John Coyle; Robert DeJager; Richard Pazdur; Leonard B. Saltz


Book ID
111579884
Publisher
Springer US
Year
2004
Tongue
English
Weight
99 KB
Volume
22
Category
Article
ISSN
0167-6997

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A Phase II study of intravenous exatecan
✍ Francisco J. Esteva; Edgardo Rivera; Massimo Cristofanilli; Vicente Valero; Mela 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 111 KB

## Abstract ## BACKGROUND The objective of the current study was to determine the antitumor activity, safety, and pharmacokinetic (PK) profile of exatecan mesylate in patients with anthracycline‐resistant and taxane‐resistant, metastatic breast carcinoma. ## METHODS All patients had clinical evi