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A phase II study of intravenous exatecan mesylate (DX-8951f) administered daily for 5 days every 3 weeks to patients with advanced ovarian, tubal or peritoneal cancer resistant to platinum, taxane and topotecan

✍ Scribed by Claire F. Verschraegen; Andrzej P. Kudelka; Wei Hu; Monique Vincent; John J. Kayanagh; Evelyne Loyer; Luc Bastien; A. Duggal; R. De Jager


Book ID
110611295
Publisher
Springer
Year
2004
Tongue
English
Weight
736 KB
Volume
53
Category
Article
ISSN
0344-5704

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A Phase II study of intravenous exatecan
✍ Francisco J. Esteva; Edgardo Rivera; Massimo Cristofanilli; Vicente Valero; Mela 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 111 KB

## Abstract ## BACKGROUND The objective of the current study was to determine the antitumor activity, safety, and pharmacokinetic (PK) profile of exatecan mesylate in patients with anthracycline‐resistant and taxane‐resistant, metastatic breast carcinoma. ## METHODS All patients had clinical evi