Forty-eight patients with advanced gastric cancer and measurable areas of malignant disease were treated with etoposide (130 mg/mz/day X 3 days) plus cisplatin (45 mg/mzday on days 2 and 3). Both drugs were given by constant intravenous infusion and repeated every 4 weeks. Common toxic reactions inc
A phase II study of combination therapy with 5′-deoxy-5-fluorouridine and cisplatin in the treatment of advanced gastric cancer with primary foci
✍ Scribed by Wasaburo Koizumi; Minoru Kurihara; Tadashi Sasai; Shigeaki Yoshida; Kimitomo Morise; Akimichi Imamura; Shugo Akazawa; Takashi Betsuyaku; Shunji Ohkubo; Hiroshi Takahashi; Toshikazu Akiya; Tsutomu Hamada; Atsushi Kiyohashi
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 513 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0008-543X
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✦ Synopsis
Background. 5'-Deoxy-5-fluorouridine (5'-DFUR, doxifluridine) is a recently developed prodrug of oral From the Japan Gastric Cancer Study Group,
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370 mg/m 2 , on Days 1-5 and 36 others in Study B received epirubicin, 30 mg/m 2 , cina Interna e Geriatria, Universita `Cattolica del on Days 1 and 5; etoposide, 100 mg/m 2 , on Days 1, 3, and 5; cisplatin, 30 mg/m 2 , S. Cuore, Rome, Italy. on Days 2 and 4; and lonidamine, 150 mg/day. ## RESULTS