A phase III randomized study of 5-fluorouracil and cisplatin versus 5-fluorouracil, doxorubicin, and mitomycin C versus 5-fluorouracil alone in the treatment of advanced gastric cancer
β Scribed by Noe Kyeong Kim; Young Suk Park; Dae Seog Heo; Cheolwon Suh; Si Young Kim; Keun Chil Park; Yoon Koo Kang; Dong Bok Shin; Heung Tae Kim; Hyo Jin Kim; Won Ki Kang; Chang In Suh; Yung-Jue Bang
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 576 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0008-543X
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To determine the feasibility and toxicity of combining leucovorin (CF) with a 5fluorouracil(5-FU) combination chemotherapy regimen currently accepted by many as standard treatment for gastric cancer, CF (500 mg/m') was administered in combination with the Georgetown S-FU, doxorubicin, and mitomycin
## BACKGROUND. Gastric carcinoma is a substantial health problem in Turkey, and the majority of patients present with inoperable disease. The aim of this randomized trial was to assess the activity of 5-fluorouracil versus etoposide when combined with epirubicin plus cisplatin in patients with adv