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A phase II and pharmacokinetic study with oral piritrexim for metastatic breast cancer

✍ Scribed by de Vries, EGE; Gietema, JA; Workman, P; Scott, JE; Crawshaw, A; Dobbs, HJ; Dennis, I; Mulder, NH; Sleijfer, DTh; Willemse, PH

Book ID
109836920
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
734 KB
Volume
68
Category
Article
ISSN
0007-0920

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A phase II study of piritrexim in combin
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✍ Everett E. Vokes; Isaiah W. Dimery; Charlotte D. Jacobs; Daniel Karp; Arturo Mol πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 468 KB πŸ‘ 2 views

Thirty patients with recurrent and/or metastatic head and neck cancer were treated with sequentially administered methotrexate (MTX) and piritrexim (PTX). The treatment schedule consisted of intravenous (IV) MTX (50 mg/m') administered on day 1 and oral PTX (75 mg/mz) administered twice daily on day