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A Phase II and Pharmacokinetic Study of Weekly 72-h Topotecan Infusion in Patients with Platinum-Resistant and Paclitaxel-Resistant Ovarian Carcinoma

โœ Scribed by Peter G. Rose; Nahida H. Gordon; Nancy Fusco; Lisa Fluellen; Michael Rodriguez; Stephen T. Ingalls; Charles L. Hoppel


Book ID
112248153
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
73 KB
Volume
78
Category
Article
ISSN
0090-8258

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Role of salvage chemotherapy with topote
โœ Ghamande, Sharad A.; Piver, M. Steven ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 56 KB ๐Ÿ‘ 2 views

## Background and Objectives: We assessed the role of salvage chemotherapy with topotecan and cisplatin in patients with platinum-and paclitaxel-resistant advanced and recurrent ovarian or primary peritoneal cancer, based on the reported in vivo and in vitro synergism between these two drugs. Meth