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A phase I trial of flavopiridol in relapsed multiple myeloma

✍ Scribed by Hofmeister, Craig C.; Poi, Ming; Bowers, Mindy A.; Zhao, Weiqiang; Phelps, Mitch A.; Benson, Don M.; Kraut, Eric H.; Farag, Sherif; Efebera, Yvonne A.; Sexton, Jennifer; Lin, Thomas S.; Grever, Michael; Byrd, John C.

Book ID
121560475
Publisher
Springer
Year
2013
Tongue
English
Weight
526 KB
Volume
73
Category
Article
ISSN
0344-5704

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Phase II trial of temsirolimus in patien
Phase II trial of temsirolimus in patients with relapsed or refractory multiple myeloma
✍ Sherif S. Farag; Shuhong Zhang; Buffy S. Jansak; Xiaojing Wang; Eric Kraut; Kenn πŸ“‚ Article πŸ“… 2009 πŸ› Elsevier Science 🌐 English βš– 508 KB

In a phase II trial, 16 patients with relapsed refractory multiple myeloma received temsirolimus 25mg I.V. weekly until progression. One partial response and 5 minor responses were observed for a total response rate of 38%. The median time to progression was 138 days. Grade 3-4 toxicity included fat