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A phase I study evaluating the safety and pharmacokinetics of weekly paclitaxel and carboplatin in relapsed ovarian cancer

โœ Scribed by A.L. LEISER; F.C. MALUF; D.S. CHI; P. SABBATINI; M.L. HENSLEY; L. SCHWARTZ; E. VENKATRAMAN; D. SPRIGGS; C. AGHAJANIAN

Book ID
109086027
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
97 KB
Volume
17
Category
Article
ISSN
1048-891X

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A phase I study of a weekly schedule of
A phase I study of a weekly schedule of paclitaxel and carboplatin in patients with advanced carcinoma
โœ Wallace Akerley; Ritesh Rathore; Neil Ready; Louis Leone; William Sikov; Howard ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 64 KB ๐Ÿ‘ 2 views

## Background: We conducted a phase i study of weekly paclitaxel (p) and carboplatin (c) in patients with advanced malignancies to determine the maximum tolerated dose (mtd) of this combination. ## Methods: Dose levels were escalated independently for patients with and without previous chemothera