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A Phase I Dose-Finding Study of Silybin Phosphatidylcholine (Milk Thistle) in Patients With Advanced Hepatocellular Carcinoma

✍ Scribed by Siegel, A. B.; Narayan, R.; Rodriguez, R.; Goyal, A.; Jacobson, DrPH, J. S.; Kelly, K.; Ladas, E.; Lunghofer, P. J.; Hansen, R. J.; Gustafson, D. L.; Flaig, T. W.; Yann Tsai, W.; Wu, D. P. H.; Lee, V.; Greenlee, H.

Book ID
121787055
Publisher
SAGE Publications
Year
2013
Tongue
English
Weight
481 KB
Volume
13
Category
Article
ISSN
1534-7354

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## Abstract ## BACKGROUND. Epidermal growth factor receptor (EGFR) and ligand expression is frequently seen in hepatocellular carcinoma (HCC). A phase 2 study was performed with cetuximab, a chimeric monoclonal antibody that binds specifically to EGFR, in patients with advanced HCC. ## METHODS.