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Phase I and pharmacokinetic study of oral thalidomide in patients with advanced hepatocellular carcinoma

โœ Scribed by Her-Shyong Shiah; Yee Chao; Li-Tzong Chen; Tzy-Jyun Yao; Jin-Ding Huang; Jang-Yang Chang; Pei-Jer Chen; Tsai-Rong Chuang; Yung-Hsin Chin; Jacqueline Whang-Peng; Tsang-Wu Liu


Publisher
Springer
Year
2006
Tongue
English
Weight
284 KB
Volume
58
Category
Article
ISSN
0344-5704

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## Abstract ## BACKGROUND. Epidermal growth factor receptor (EGFR) and ligand expression is frequently seen in hepatocellular carcinoma (HCC). A phase 2 study was performed with cetuximab, a chimeric monoclonal antibody that binds specifically to EGFR, in patients with advanced HCC. ## METHODS.